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Antibody Research

1 min read

Generation Using a Molecular Modeling Platform to Guide Therapeutic Antibody Discovery

By Antibody Solutions Research Team on Dec 9, 2019 10:40:00 AM

"Using a Molecular Modeling Platform to Guide Therapeutic Antibody Discovery” details the integration of advanced 3-D modeling tools for the analysis of proteins and antibody-antigen interactions in our discovery platform. We show that adding molecular 3D modeling to the mix can reduce the cost and time of antibody discovery. 

Topics: Transgenic Animals Posters Human Therapeutic Antibodies Immunization
1 min read

Optimization of Therapeutic Discovery Strategies for Human Antibody Transgenic Animal Platforms

By Antibody Solutions Research Team on Apr 8, 2018 10:55:00 AM

Immunization of transgenic animals producing human antibodies has been the most successful approach to obtaining fully human therapeutic antibodies. They allow for the rapid generation of candidate antibodies to multiple targets of interest and the ability to transition lead candidates to clinical development without undergoing time consuming and costly steps such as humanization or affinity maturation of antibodies from structural display libraries.

Topics: Transgenic Animals Posters Human Therapeutic Antibodies