Immunogenicity/ADA Reagents and Assays


Biologics (e.g., drugs composed of a protein or antibody) typically provoke a host antibody response when the drug is administered to animals or humans. The production of antibodies to the biologic will require reagents, positive controls, and the development of an assay that can measure anti-drug antibodies. Depending upon the format of the assay, the drug may need to be conjugated to enable detection of anti-drug antibodies. Additionally, a positive control is required to demonstrate the sensitivity of the assay.

Antibody Solutions has a proven track record of generating drug conjugates, affinity-purified polyclonal antibodies and drug-specific monoclonal antibodies. Assay method development is also available. We offer antibody and assay development solutions that match your specific immunogenicity / ADA challenge.