PK/PD Antibodies and Assays

In drug development, Pharmacokinetic (PK) analysis of the drug is performed to determine the fate of the drug (e.g., distribution, absorption and/or secretion) after administration to an animal or human. This analysis is often carried out in conjunction with Pharmacodynamics (PD), the study of a drug’s pharmacological effect on the body. The PK and PD assays typically require critical reagents (e.g., specific anti-drug antibodies) and the development of an assay that can measure the drug in plasma and tissues.

Antibody Solutions has a proven track record of generating drug-specific monoclonal antibodies, affinity-purified polyclonal antibodies, and related reagents for PK and PD analysis. Assay method development is available as well as research-level dosing studies in rodents.