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Science

Research Library

Research-Based, Research-Focused

At our core, we are scientists committed to advancing research that helps bring safer, more efficacious therapeutics and diagnostics to the patients who need them more quickly. As part of that mission, we maintain an active research and publishing program to share insights and information gleaned from our work with our peers.

Below is a list of scientific posters and publications that were either authored by a member of the Antibody Solutions team, contain information about our firm or pertain to services we performed for clients.

If you would like a copy of any article or would like to discuss our findings, please don’t hesitate to get in touch with us via email (solutions@antibody.com) or phone (888.843.1069).


Scientific Posters

1 min read
Antibodies Targeting Three Spike Protein Domains Regulating SARS-CoV-2 Infectivity

Infectivity of SARS-CoV-2 is regulated by three sites on the spike protein: a receptor binding motif (RBM), a subunit...

1 min read
Generation of Antibodies to Difficult Membrane Protein Targets

Multipass transmembrane and multimeric membrane proteins are targets for the development of therapeutic monoclonal...

1 min read
Optimization of Therapeutic Discovery Strategies for Human Antibody Transgenic Animal Platforms

Immunization of transgenic animals producing human antibodies has been the most successful approach to obtaining fully...

1 min read
Generation of Neutralizing Human Monoclonal Antibodies Against a Therapeutic Target from the Alloy Therapeutics Mouse

Immunization of transgenic animals producing human antibodies is the most successful approach to obtaining fully human...

1 min read
A Rapid, High-Throughput Recombinant Antibody Expression System for Therapeutic Antibody Discovery and Validation

Hybridoma cell lines have historically offered an efficient, low-cost means to produce large numbers of monoclonal...

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Development of a Defined Cloning and Growth Factor Formulation for Murine Hybridomas

Conditioned media from cultured cells have long been used to increase the cloning efficiency, growth rate and antibody...

Publications

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HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both its Translation and Intracellular Stability

The human immunodeficiency virus type 1 (HIV-1) relies on Vif (viral infectivity factor) to overcome the potent...

2 min read
Chemical Synthesis and X-ray Structure of a Heterochiral {D-protein antagonist plus vascular endothelial growth factor} Protein Complex by Racemic Crystallography

Total chemical synthesis was used to prepare the mirror image (D-protein) form of the angiogenic protein vascular...

1 min read
Modulation of Lysyl Oxidase-like 2 Enzymatic Activity by an Allosteric Antibody Inhibitor

In this report, we assessed the steady-state enzymatic activity of lysyl oxidase-like 2 (LOXL2) against the substrates...

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DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency

Previous studies have shown that blocking DLL4 signaling reduced tumor growth by disrupting productive angiogenesis. We...

Cadherin-11 Antagonists and Methods for the Treatment of Inflammatory Joint Disorders

The present invention relates to Cadherin-11 antagonists and compositions comprising Cadherin-11 antagonists. The...

1 min read
ARMER, Apoptotic Regulator in the Membrane of the Endoplasmic Reticulum, a Novel Inhibitor of Apoptosis

We have identified a novel protein, apoptotic regulator in the membrane of the endoplasmic reticulum (ARMER), which...